You need a minimum of 2 1000w's .....most of these guys will most likely tell you 4 1000's or more, but a 1000w could effectively cover a 5x5 area (by what I have seen and read) and you basically have 4 of those. The more light the better! Also, I see that 7800 lumens per square foot is a nice number to get nice plants with nice yields. Some push 10,000 + per sq'. I personally would do something like make 4 rooms.
-Split the 10' Length in 1/2
-Measure 1' each way from center
That will give you a 2' Walkway. I'm not sure if you will need more than one walkway, but if you do, just do the same with the width. If you do that you will end up with 4 - 4x4 rooms. This way you could do different things - breed, grow different strains, perpetual, etc. This would also give you excellent lighting ....over 9000 lumens per sq'.
You also have the option of using some circular light movers. You could run 2 of those in one open area or even split the area in 2 and have one in each.
And if you have the money and you set-up your electricity properly, you can go vertical and use more lights, but the yields and plants are amazing. I would do a search on vertical and see what you come up with.