It’s been since the 80’s.
If we went up, came down. Next hit didn’t work

took a day or two
We were probably crash test dummies
Pretty much all serotonin receptor based psychedelics build tolerance stupidly fast. If you eat mushrooms too often they completely stop doing anything at all but making you fart, pretty much entirely lol.
You could take a tab of the finest, cleanest paper around today. And if you ate more in the next 24-48 hours you would need significantly more to have the same effect. If you ate another tab right after coming down, yea prob wouldnt do much of anything but keep you awake. There have been some bizarre research chems over the years too, and now a days, there are some that are basically impossible to tell apart from decent L if you arent super experienced with em, that are actually incredibly toxic, potentially lethal substances. I dont even recommend considering consuming psychedelics on paper in this day and age unless you have the proper reagents to know exactly what you have.
An active dose of some of these things, are 50/1000ths of 1/1000th of a single gram of material. Doses are measured in micrograms. This is comparable to a roley-poley demolishing the Empire state building in 30 minutes flat. It's not even comprehensible for me personally. It's like rationalizing a black hole or something. Serotonin receptors attract these compounds like iron shavings to a high powered magnet as if the substance of our bodies were not even there. We only even know serotonin receptors exist and are fundamental to the formation of consciousness because these substances exist. But they are illegal, creating a total void of research that would be all but guaranteed to propel us into a golden age of understanding the human condition and our own psychology and consciousness, and also a very dangerous black market.
I can def say i had some guinea pigs over the years, some willing, some just looking for a good time. If you aren't flipping it these days, but buying it, you've probably been guinea pigged on multiple occasions by someone who wasnt entirely sure what they had.
Mushrooms are great. I like mushrooms. Psilocybin is just orally active DMT and it's even less toxic then THC, and they're un-abusable by nature's own wish. You can trust psilocybin mushrooms, and once you've seen one in person, youll recognize them all.