Well I guess this all depends on how good you are with the tool bag,,me,,Id put in minisplits for the four bays youl be growing in the mother/clone room wont need to many BTU's most likely, need to lnow the deet's on lighting in there the mini split condensers can be set in the open bay but that space will need to be air exchanged to not allow condensing temps to go much above 90 to maintain efficiency (lots of ways to do this).gives you stealthy quiet coling in all area's By what you said about the bldg const. You should bring down that ceiling to 8' or so to prevent stratafacation and heat build up up high digging into the efficiency some more If your going to vent the lighting through the room and not from the room id go 18,000(1 1/2 ton) for the 8K bays and if your sure that your not gonna need more in the future for the 4K bay then go 12,000(1 Ton) and assuming mild load in the mother closet go 6,000 btu. Evin if you have a lighting ventalation failure those capacaty units should be able to easly handle the entire load but will run normally for humidty control with proper ventalation of lighting ..If you can braze copper, twist some wires and run a vacume pump or have a fraind who can this would ideal dont let people scare ya into not trying if you feel yourself compentant, but done embark on something you know you cant do,,wiring's no hobby,,but its not to diffacult,as far as brand if money really is no problem then Trane,of course, but cheaper brands are out there mitsubishi,sanyo, Its true the new 410a refridgerants require and bit tighter dissapline than the old 22 systems but a freon burn is a freon burn, you learn fast,,you also can get the line sets precharged at 25' and 50' lengths with some models the bigest advantage to this setup is if you have a cooling problem its localized and with a little mcguyver ducting you can limp along of the others..and onthing is visable from outside nor is there much noise from them at all
