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"The surprising result of our study was the absence of any kind of analgesic activity of THC-standardized cannabis extract on experimentally induced pain using well-established human model procedures," study author Dr. Birgit Kraft said in a prepared statement. "Our results also seem to support the impression that high doses of cannabinoids may even cause increased sensitivity in certain pain conditions."
As you study suggest, the oral comsuption work most effective due to the resulting cannaboid produced onec passed through the liver. where as with weed it becomes alot more difficult to tell which is more prodominent in the shit you got, THC, CBN or CBD.
Oral def allows for a more effective approach in reducing this control factor down to a single cannaboid, which its clear we all agree is the reason why this study is an epic PHAIL.
Ja man, what i said was that this worked effective becuase, unlike smoking, when you eat and it passes through your liver producing the required cannaboid, you are guranteed said cannaboid (hydroxy Eleven), instead of THC, CBN etc.
How much would you administer each pill? do you just grind it up, or make some ice 1st?
Thats an interesting approach, however, from a clinical stand point, i dont think they would accept this. One thing wich studies are looking for is to get a positive response while using specific techniques that reduce any phsychoactive effects. Im assuming that these patients still got high from these pills?
Indeed, even as the study suggests, dosing becomes very difficult. Even with set groups the tolerance levels will differ, as you said. But could you imagine the difference between a 1st time user and a recreational user for 10 years. I think 10-1 would be a sufficient ratio for pills required.
Even removing psychoactive properties means removing certain compounds, no longer making it whole Cannabis. So I do not believe science will ever be able to create a medicine that can exactly duplicate the effects of whole Cannabis. Not to mention, the psychoactive effect is what certain patients require to aid them. So whether science accepts this really isn't the point. The point still is whole Cannabis is the best form for patients to use.
Well under medical supervision the dosage would be only a hit or two from a pipe, or maybe something around 25mg or even 15mg with the whole Cannabis pills. And since every person, regardless of dose, will react different they have the ability to judge whether they need more or not with no worry of a side effect more than being a little high. Who knows they might like being a little high anyway.
Think of when you first smoked pot, a few hits would last hours, and even sativas would knock you on your ass
I agree entirely, however, unfortunetly as you are mots likely aware, there is currently a war on weed. THis war makes an attempt to belittle Cannabis as a mere street drug used by kids and students as a stepping stone to harder drugs. With that comes the stupid belief in anything that gets you high is bad.
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