What are general conditions? Light, feeding, etc?

It sure looks like insect damage, especially the spots. Later on, the spots sort of merge and create holes. It's possible that there were bugs at one time but were killed off or something. My lastest clones had mites but before I planted them I treated them with a hot shot no pest strip in a box for a few hours.... it will kill just about anything. Lately I noticed the dreaded spots on the leaves, but then realized these were older leaves that kept growing, but were originally infected with spider mites. All of my damage is on the lower and older leaves with new growth looking fine. Just a thought.