The viscosity difference would probably be the biggest issue, although better cartridges handle thicker compounds better than cheap ones. Cutting the distillate with anything will minimize it's THC concentration, plus who wants to smoke PEG or similar stuff? I'm not familiar enough with either process to recommend one over the other, although the distillate sounds more like a combination of dry fractional distillation and CO2. Both pull different compounds separately, like
Terpenes and THC, it's mostly a matter of purity by the looks of it, with CO2 extraction pulling more things together and having lower THC levels with all things combined. These things you probably already know.
The biggest issue is to get the thick, sludgy stuff to flow in