You cant use a house a/c and run a closed system as far as a room, you have to make the whole house the closed system.
If you try to seal up your room and cut your air on the pressure will build up in your room and most likely break any seals you make to inclose it.
I got some pix saved of someone elses set-up Ill post to help give you ideas....
1st pic is co2 unit infront of central air intake
2nd pic showing how he pulled air out of the room while killing smell
3rd pic shows him cooling the grow room.