i guess it depends on what you want it for . i use oil made from a plant called painkiller which is 10% cbd and 8% thc. i also make high thc oils, and come fall, when i get the candida plants going, i'll have cbd at about 18-20 % and almost no thc.very good for pain relief.i would make it as strong as you can and then moderate the dose.i make it full strength and take it as required ,which for me is twice a day.i'm treating cancer so i take a shitload.it depends on whether you are new to this, or are a seasoned smoker like myself.if you're new, be careful how much you start with as it can knock you on your ass.