I tend to KISS and listen to what the CCH2O literature says. For you folks with root problems are you doing the following (assuming your water is good):
1. Keeping solid aeration at 1 liter per minute of air per gallon of water?
2. Using a water chiller to keep root temps 65-68 degrees?
3. Using a preventative product like UC roots?
If your Nutes are clean, the plants are strong and come from a sterile background - I don't see why sterile shouldn't work every time. I more subscribe to the sterile line of thought as we are feeding the plants very low PPM of chemical Nutes. We don't need a whole lotta 'beneficials' and such as the food for are plants is already broken down and ready for them. These things can gunk up our system.
I think of a river or waterfall when I open my buckets. I want highly aerated, cool and crystal clear solution. I'm not saying it is the only way but I like to KISS. UC roots is expensive ($100/gallon) but at 2 ml/gallon/week is that worth a harvest to you? Seems to me to be chlorine without the sodium. Stable hypochlorous acid, whatever it works.
Check out the CCH2O growers guide here, in specific section 14 and 24.
http://cch2o.com/rdwc-hydroponics-growers-guide/
Not gonna lie, I'm a fan of CCH2O because they have created not only a streamlined system but simplified nute regime to back it up. If I wasn't running their stuff id probably be rocking something real clean like HG aqua flakes or Ionic with H2O2. I rock a small system and the ROI and simplicity of CCH2O is a no brainier for me. $500 for a gallon of everything? Sold. (Excluding the early/late bloom, I just use mid)