Yes but I think it makes for a superior product.greywolf here posting above is literally THE guy on the forums for extracts and he uses ISO so if he does it's surely gotta be worth it.
I will probably give ISO a go aswell.i would actually probably be better served doing ISO as it seems it would cost less to do it.
May I put QWISO into perspective from my view, starting with the observation that the fish trap exists only because of the fish, and the fish is more important than the design of the trap?
My preferred form of extraction for most purposes is using a non polar solvent like Butane in a closed loop system, or QWET using 190 proof Ethanol and recovering the alcohol for reuse.
Those choices are based on on a number of factors in part related to their intended use and cost per gram to produce a quality product. Also because Butane is rated as GRAS by the FDA, allowing its use as a food propellant, and Ethanol is of course food grade, so you can leave more of it than ISO, even if FDA standards are the same.
Add to that the element of choice, which is because I can.
Not everyone is in a position to use BHO or obtain 190 proof Ethanol, which begs the question of what does a patient use if they can only get something like 99% Iso?
My answer is that Iso is also listed as a Class III solvent by the FDA, meaning they limit it to 5000 ppm in pharmaceuticals and food. It is also a pungent alcohol, detectable by most folks senses below 500 ppm.
Sooo, if I can keep it below 500 ppm and produce a medication that gets the job done, with the alternative to not get the job done, not much of a leap for me. I have made, used, and taught Iso, and it actually got high marks with the volunteer student testing panels after classes making it.
I also do a number of other types of extraction, depending on availability of supplies and end product desired. For some purposes VG, or cooking oils are just the ticket. IE: Just 15% saturation in vegetable oil makes a killer pain relieving topical. I currently use a 15% solution, in a commercial off the shelf joint and muscle relief oil, which works even better.
For small dabbing quantities, consider pressing Rosin...... Etc